Ready to prescribe LUMRYZ? Here’s what you need to know

As with other oxybate medications, you must be REMS-certified in order to prescribe LUMRYZ.

Flexible enrollment to get patients started with RYZUP™ Support Services and LUMRYZ REMS

Our integrated enrollment process ensures documents are delivered to the correct location to help support your patient’s care.


Choose from 1 of the 3 options below:

Start at RYZUPConnect.com, and then navigate to LUMRYZ REMS portal from there.

A one-time prescriber registration with HCPverify.com allows you to download, e-sign, and submit the LUMRYZ Prescription Form electronically.

In addition to eRx, you may be able to call in a verbal order or fax in a written Rx. The prescriber is to comply with state-specific prescription requirements such as e-prescribing, state-specific prescription form, fax language, etc.

Fax all documents to the LUMRYZ fax number: (877) 206-3198.

All papers/forms can be scanned, saved, and submitted to RYZUPConnect.com. (No login required)

A one-time prescriber registration with HCPverify.com allows you to download, e-sign, and submit the LUMRYZ Prescription Form electronically.

In addition to eRx, you may be able to call in a verbal order or fax in a written Rx. The prescriber is to comply with state-specific prescription requirements such as e-prescribing, state-specific prescription form, fax language, etc.

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Support for every new patient start

A Field Reimbursement Manager can provide a step-by-step in-service to help support you with your patient starts and throughout the process. This includes reviewing all financial assistance eligibility criteria and other program information with you in detail.

Call (844) 485-7636 to be connected with RYZUP Support Services or click below to hear from a Field Reimbursement Manager.

Connect with a Field Reimbursement Manager

LUMRYZ dispensing pharmacies

Optum Frontier Therapies 
Fax: (844) 371-7787 
Phone: (877) 851-0010
Accredo 
Fax: (877) 325-3878 
Phone: (800) 424-2618
CVS 
Fax: (844) 691-1346 
Phone: (800) 834-2806
AssistRx (non-commercial only) 
Fax: (913) 227-4203 
Phone: (913) 396-7696

Review financial assistance programs

eRx, electronic prescription; REMS, Risk Evaluation and Mitigation Strategy; Rx, prescription.